Do hyaluronic acid (knee gel) injections work for knee pain?

Many patients with knee osteoarthritis experience reduced pain and improved mobility after hyaluronic acid injections, particularly in moderate cases.

How long do knee gel injections last?

Results typically last between 6 to 12 months depending on the severity of knee osteoarthritis and individual response.

Are hyaluronic acid injections painful?

Most patients report only mild discomfort during the procedure. Ultrasound guidance improves accuracy and reduces unnecessary discomfort.

How quickly do knee gel injections work?

Improvement is usually gradual, with most patients noticing benefits within 2 to 6 weeks after treatment.

Do I need a GP referral for knee injections?

No GP referral is required. Patients can book directly for assessment and treatment if appropriate.

Ultrasound-Guided Hyaluronic Acid Joint Injections for Pain Relief

Hyaluronic acid (knee gel injections) for long-lasting relief without surgery

      EXCELLENT  
   Based on 321 reviews 
    
 
 
 
   
 
 
       Posted on Google  
   
   Alison Hunt 
 
 
 
 Trustindex verifies that the original source of the review is Google. I saw Marek again for an ultrasound steroid injection for my bursitis.  He checked through my notes before arranging an appointment making sure this was ok. When I arrived he was friendly but very professional.  He checked where my pain was and whilst injecting me kept asking how I was. After the procedure we chatted about alternative procedures for the future which was good.  Would definitely recommend Marek
  
 
      Posted on Google  
   
   Paul Conneely 
 
 
 
 Trustindex verifies that the original source of the review is Google. In extreme pain following a rheumatic flare I desperately searched in vain for a steroid injection to my wrist through various NHS providers.  In desperation I contacted Physio-Soton and was seen the next day.

The service and results were second to none. I received an Ultrasound guided steroid injection and felt immediate relief and the joint has got better each day since.

As most people under rheumatology know getting help quickly is almost impossible so this service is a lifeline for those in severe pain and I could not recommend it highly enough.

Going from 10/10 pain to mild discomfort in the space of a day is remarkable and Physio-Soton will be the first port of call in future. I am forever grateful for the level of service and clinical expertise.
  
 
      Posted on Google  
   
   Ross Mitchell 
 
 
 
 Trustindex verifies that the original source of the review is Google. Personally I've often been sceptical of reaching of for scans or therapy work due to poor past experiences, however I can say upon visiting Marek this is one of the few places I've been that offer a great service.

Clear and direct feedback with open communication made the appointment flow smoothly.

I'd highly recommend for anyone who's got some niggles or injures that just don't seem to be healing and you need to know/understand what's going on.

****** 6 stars as google only offers 5.
  
 
      Posted on Google  
   
   Karen Aston 
 
 
 
 Trustindex verifies that the original source of the review is Google. Had a same week appointment with Marek to have an ultrasound on my ankle where I had concerns of a long ongoing achilles complaint. Marek was very thorough in his assessment and recommended exercises to help relieve. He also provided a thorough report and copies of the scans to share with my GP and NHS specialist I am under. Would definitely recommend
  
 
      Posted on Google  
   
   SW Southern Karate 
 
 
 
 Trustindex verifies that the original source of the review is Google. I would highly recommend Marek. He’s very professional and approachable. I went to see him with shoulder pain. He did an ultrasound and then administered an injection. Went through everything really well so I knew what to expect during and after the procedure. I will definitely be seeing him again.
  
 
      Posted on Google  
   
   Tim Ponsford 
 
 
 
 Trustindex verifies that the original source of the review is Google. I initially saw Marek after suffering a sporting injury to my right bicep, elbow and shoulder. He was referred to me by my chiropractor as I was keen to get an ultrasound as quickly as possible. Marek offered me a next day appointment and spent an hour conducting a full and thorough ultrasound of the soft tissue and joints in the affected areas. He was very reassuring and professional, taking his time to explain everything clearly and making sure I understood what he diagnosed. I left feeling much happier and with a clear understanding of what I needed to do to recover.

A second follow up appointment built on the first, more reassurance and new exercises to help build up strength and confidence.

Overall I would highly recommend Marek. He is calm, reassuring, professional and patient. Thank you!
  
 
      Posted on Google  
   
   James 
 
 
 
 Trustindex verifies that the original source of the review is Google. Extremely happy and impressed. For context, I am a 21 year old male who contacted Marek due to acromioclavicular joint issues due to weightlifting. He was able to book me in a few days from my phone call with him. All my questions were answered in a detailed and informative manner, and the aftercare was great as he phoned me later in the day after reviewing my ultrasound images. The most important thing to note is his moral integrity which I was so surprised with due to how many people are today. Because of my issue I thought I would need a joint injection, however he said for my case this would be unnecessary and potentially delay healing. This is surprising as many practitioners these days would advise having the injection merely to make a buck off of me. I really respect this honesty and truthfulness. Thanks very much.
  
 
      Posted on Google  
   
   Ruth Clifford 
 
 
 
 Trustindex verifies that the original source of the review is Google. Thank you Marek! A comprehensive scan and explanation of my ankle issue with advice for self recovery and exercises moving forward. Most helpful. I would have no hesitation in recommending your service to others. Quick and easy to book an appointment online.
  
 
      Posted on Google  
   
   Matt Webster 
 
 
 
 Trustindex verifies that the original source of the review is Google. Excellent experience with Marek at Physio-Soton. I came in with a long-running Achilles problem and he took a proper history, reviewed my training, tested the tendon thoroughly with Ultrasound — diagnosis, imaging and a clear rehab advice all in one visit. He was honest about what the findings meant for my running rather than telling me what I wanted to hear, and explained everything in plain terms. As a triathlete it's rare to find a physio who is also an MSK sonographer and genuinely understands training load. Highly recommended.
  
 
      Posted on Google  
   
   Charlette Mitchell 
 
 
 
 Trustindex verifies that the original source of the review is Google. I had an excellent experience with Marek following my car accident. From the initial phone call through to my appointment at the clinic, he was professional, well spoken, and took the time to explain everything clearly, which immediately put me at ease.

He carried out a detailed ultrasound scan of my shoulder, and having access to advanced diagnostic equipment within the clinic meant the assessment was thorough and precise. He clearly explained the findings, what they meant, and the treatment options available, giving me a much better understanding of my injury.

Marek is highly experienced, exceptionally knowledgeable, and genuinely focused on providing the best care for his patients. His professionalism, expertise, and attention to detail were outstanding. I would highly recommend Marek to anyone looking for an accurate diagnosis and first-class treatment.
  
 
  
  
 
     Verified by Trustindex  Trustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more

Why Choose Physio Soton for Hyaluronic Acid Injections in Southampton?

Choosing the right clinic for your injection is important — accuracy, clinical assessment, and timing all influence your results.

✔️ Ultrasound-Guided Injections
All injections are performed under ultrasound guidance to ensure precise placement, improving effectiveness and safety.

✔️ Fast Access to Treatment
Avoid long NHS waiting times with timely assessment and treatment when appropriate.

✔️ Same-Day Appointments (Where Suitable)
In many cases, assessment and injection can be completed in the same visit to speed up recovery.

✔️ Direct Booking – No GP Referral Needed
You can book directly with us without needing to see your GP first.

✔️ Initial Consultation – £60
Includes full assessment and expert advice on whether an injection is appropriate for your condition.

✔️ Clinically Appropriate Care
We follow recognised clinical guidelines, ensuring injections are only recommended when they are likely to benefit you.

Hyaluronic acid injections for knee pain in Southampton — We use many diffrent types of hyaluronic acid injections in our clinic in Eastleigh near Southampton.

Ultrasound-Guided Injections for Accuracy and Safety

All injections at our clinic are performed using ultrasound guidance.

This allows us to:

Precisely guide the injection into the knee joint
Avoid surrounding structures such as tendons and blood vessels
Improve accuracy compared to landmark-guided injections
Increase the likelihood of effective treatment

Ultrasound guidance is considered best practice for joint injections and helps ensure you receive the treatment as safely and effectively as possible.

Long-lasting relief for knee pain without surgery

If you’re struggling with ongoing knee pain, hyaluronic acid injections (often called knee gel injections) can help reduce pain, improve movement, and get you back to doing the things you enjoy.

✔ Reduce pain and stiffness
✔ Improve walking and mobility
✔ Non-surgical treatment option
✔ Delivered by experienced MSK clinicians

👉 Book your consultation today

Struggling with Knee Pain in Southampton?

Knee pain can affect every part of daily life.

You might notice:

Pain when walking or standing
Difficulty climbing stairs
Stiffness after sitting
Reduced ability to exercise
Ongoing discomfort despite physiotherapy

If this sounds familiar, you’re not alone — and there are effective treatment options available.

What Are Knee Gel Injections?

Hyaluronic acid is a naturally occurring substance in your joints that helps with lubrication and shock absorption.

In people with knee arthritis, this substance is reduced.

A hyaluronic acid injection helps to:

Improve joint lubrication
Reduce friction in the knee
Ease pain and stiffness
Support smoother movement

This treatment is commonly used for people with knee osteoarthritis who want to avoid or delay surgery.

Who Are These Injections For?

You may be suitable if you:

Have been diagnosed with knee osteoarthritis
Have ongoing knee pain despite physiotherapy
Want to avoid or delay surgery
Are looking for longer-lasting relief than painkillers

Not sure if it’s right for you?

👉 Book a consultation and we’ll assess your knee and guide you through your options.

Hyaluronic Acid vs Steroid Injections

Understanding your options is important.

Steroid injections:

Fast-acting pain relief
Typically lasts a few weeks to months

Hyaluronic acid injections:

Slower onset (usually 2–6 weeks)
Longer-lasting relief (often 6–12 months)
Helps improve joint function as well as reduce pain

We’ll help you decide which option is most appropriate for your condition.

Hyaluronic acid versus steroid injections — Durolane is a very good hyaluronic acid injection for the knee arthritis. It can be combined with steroid injection.

What to Expect

Consultation:
We assess your knee, symptoms, and suitability for treatment.

Procedure:

Takes around 15–30 minutes
Quick and minimally uncomfortable
Performed in clinic

Aftercare:

Walk out the same day
Return to normal activities shortly after

Results:

Gradual improvement over several weeks
Pain relief can last several months

Cost of Knee Injections

Initial consultation: £60
Injection (includes consultation): From £350

✔ Transparent pricing
✔ No hidden costs

👉 Contact us if you’d like to discuss pricing before booking

Local Clinic – Southampton & Eastleigh

We are based in Eastleigh and regularly treat patients from:

Southampton
Eastleigh
Chandler’s Ford
Winchester
Across Hampshire

✔ Easy access location
✔ On-site parking available

Frequently Asked Questions

Do knee gel injections work?
Many patients experience reduced pain and improved mobility, especially in moderate knee arthritis.

How long do the injections last?
Relief typically lasts between 6–12 months, depending on the individual.

Are the injections painful?
Most patients report only mild discomfort during the procedure.

How quickly do they work?
You may start noticing improvement within 2–6 weeks.

Can I avoid surgery with this treatment?
In many cases, injections can delay or reduce the need for surgery.

Ready to Reduce Your Knee Pain?

If knee pain is affecting your daily life, this treatment could help you move more comfortably again.

👉 Book your consultation today
👉 Speak to a clinician about your options

About author

Marek Czeladzki is a chartered physiotherapist (HCPC and CSP registered), independent prescriber (IP), and musculoskeletal sonographer – a member of both the British Medical Ultrasound Society and the American Institute of Ultrasound in Medicine. Marek completed studies in ultrasound guided injections for joints and soft tissues at the University of Essex. He also completed intensive studies in myoskeletal therapy. He treats patients with spinal, joint and muscle injuries including sports injuries.

Trusted Patient Resources: Hyaluronic Acid Joint Injections

NHS – Osteoarthritis Overview
Explains osteoarthritis, the most common condition treated with hyaluronic acid injections, and outlines standard treatment options.
Arthritis Foundation – Hyaluronic Acid Injections
Explains how “gel injections” work, expected benefits, and typical duration of symptom relief.
Johns Hopkins Medicine – Viscosupplementation
Medical explanation of how hyaluronic acid injections improve joint lubrication and reduce pain in osteoarthritis.
Bupa – Hyaluronic Acid Injections
Patient-facing UK clinic information covering what to expect before, during, and after the procedure.
Benenden Hospital – Durolane Injection Information
Explains single-injection hyaluronic acid treatments and how they help restore joint lubrication.
Mayo Clinic – Hyaluronic Acid Injection Overview
Clinical overview of use, side effects, precautions, and administration.

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297 High Street, Eastleigh, SO50 5NB