- 023-8218-2416
- info@physio-soton.co.uk
- 297 High Street, Eastleigh, SO50 5NB
- Opening hours: Mon - Fri 10:00 - 20:00, Sat 10:00-15:00
If knee pain, stiffness or reduced mobility is affecting your everyday life, you may be looking for an effective non-surgical treatment for knee osteoarthritis.
KioMedine® one is a modern, single-injection medical device designed for the symptomatic treatment of knee osteoarthritis in adults. It is injected directly into the knee joint by an appropriately experienced healthcare professional.
For patients in Southampton, Eastleigh and across Hampshire, KioMedine may provide another treatment option to consider as part of a personalised approach to managing painful knee osteoarthritis.
Book a consultation to find out whether KioMedine is suitable for your knee.
[BOOK A KioMedine CONSULTATION]
KioMedine® one is a single-injection fluid implant designed to supplement the synovial fluid within an osteoarthritic knee.
It contains a specially developed form of carboxymethyl-chitosan (CM-chitosan), an animal-free biomaterial derived from button mushrooms.
The product is designed to:
improve lubrication within the knee joint
reduce friction between joint surfaces
help protect the synovial environment
provide symptomatic relief from knee osteoarthritis
KioMedine is a regulated medical device and should only be administered by an appropriately qualified healthcare professional experienced in intra-articular injections.
Knee osteoarthritis can cause much more than occasional discomfort.
You may experience:
Pain when walking
Pain when climbing or descending stairs
Knee stiffness
Difficulty getting up from a chair
Reduced ability to exercise
Pain after periods of activity
Difficulty with everyday activities
A feeling that your knee is becoming increasingly limiting
If conservative treatments have not provided enough relief, an injection-based treatment may be worth discussing with a suitably qualified clinician.
KioMedine is intended for adults with symptomatic knee osteoarthritis. Whether it is appropriate for you depends on your individual symptoms, diagnosis, medical history and examination.
The knee normally contains synovial fluid, which helps lubricate the joint and reduce friction.
With osteoarthritis, changes within the joint can affect this environment and contribute to pain, stiffness and reduced function.
KioMedine® one is designed to act within the joint by providing lubrication and reducing friction. Its CM-chitosan biomaterial also has properties intended to help protect the joint environment.
The aim is not simply to mask knee pain, but to support the joint environment while helping to relieve symptoms associated with osteoarthritis.
One of the features of KioMedine® one is that it is designed as a single intra-articular injection.
Your clinician will first assess your knee and discuss your symptoms, previous treatments and suitability for injection.
If KioMedine is considered appropriate, the treatment is administered directly into the knee joint.
Your clinician will explain what to expect before and after the procedure and provide personalised aftercare advice.
Your appointment should begin with a proper assessment rather than simply proceeding directly to an injection.
We will consider:
We will discuss where your pain is, when it occurs and how it affects your daily activities.
It is important to establish whether your symptoms are consistent with knee osteoarthritis and whether an injection is an appropriate treatment option.
We can discuss treatments you have already tried, including exercise, physiotherapy, medication or previous injections.
Treatment should be guided by what you want to achieve — whether that is walking more comfortably, returning to exercise, improving day-to-day mobility or managing symptoms while considering your longer-term options.
Your clinician will consider your medical history and whether there are any reasons why KioMedine may not be appropriate.
There are several different types of injection used in the management of knee pain and osteoarthritis.
These can include treatments such as corticosteroid injections, hyaluronic acid-based injections and other regenerative or biologic approaches.
KioMedine is different because it uses a proprietary carboxymethyl-chitosan biomaterial and is designed as a single-injection fluid implant.
There is no single injection that is right for every patient.
The most appropriate option depends on factors such as the severity and pattern of your osteoarthritis, your symptoms, previous treatments, general health and treatment goals.
During your consultation, we can discuss the available options and whether KioMedine is appropriate for you.
Clinical research has evaluated KioMedine® one in adults with symptomatic knee osteoarthritis.
The manufacturer reports results from clinical studies including the PIONEER study, with follow-up data published in Osteoarthritis and Cartilage Open in 2025.
The reported research has investigated changes in knee pain and other osteoarthritis symptoms following a single injection.
Importantly, individual results vary. Clinical evidence should be considered alongside a proper assessment of your knee rather than interpreted as a guarantee of a particular result.
Everyone responds differently to treatment.
Clinical information published by the manufacturer reports improvement in symptoms in some patients during the weeks following treatment, with benefits observed over longer follow-up periods in clinical studies.
Your clinician will discuss realistic expectations with you based on your individual circumstances.
KioMedine should not be viewed as a guaranteed cure for osteoarthritis.
The duration of benefit varies from person to person.
Clinical follow-up has assessed patients over periods of up to 12 months, with the manufacturer reporting sustained symptom improvement in some patients.
However, there is no way to guarantee how long an individual patient will experience benefit.
Your underlying osteoarthritis, activity levels, general health and other factors can all influence your symptoms over time.
Following treatment, you will receive specific aftercare advice.
The manufacturer’s patient information recommends avoiding intense physical activity and heavy loads for 48 hours after the injection, followed by a gradual return to normal use of the treated knee.
Regular appropriate exercise remains an important part of managing knee osteoarthritis.
If you develop persistent pain, significant swelling or other unusual symptoms following an injection, you should contact your healthcare professional.
No.
KioMedine is intended for adults with symptomatic knee osteoarthritis, but it is not appropriate for everyone.
The manufacturer’s information lists a number of contraindications and precautions, including certain allergies, infection or skin disease around the injection site, severe inflammation or synovitis, inflammatory arthritis, certain autoimmune or crystal diseases, significant vascular or blood disorders, pregnancy or breastfeeding, and being under 18.
This is why a proper clinical assessment is essential before treatment.
We provide access to specialist knee assessment and injection treatment for patients looking for options for painful knee osteoarthritis in Southampton, Eastleigh and the surrounding Hampshire area.
Our location makes treatment convenient for patients travelling from:
Southampton
Eastleigh
Chandler’s Ford
Hedge End
Winchester
Romsey
Totton
Fareham
Hampshire and surrounding areas
If you are searching for KioMedine in Southampton, KioMedine in Eastleigh or a knee osteoarthritis injection in Hampshire, we can assess your knee and discuss whether this treatment is appropriate for you.
An injection is only one part of treating osteoarthritis.
A good treatment plan should consider the whole picture — your symptoms, diagnosis, physical function, previous treatment and longer-term goals.
Our approach is therefore focused on helping you understand:
What is causing your knee pain?
What treatments have you already tried?
What options are available to you now?
Could KioMedine be appropriate for your knee?
What should you consider for your longer-term joint health?
The aim is to give you clear, evidence-informed advice so you can make an informed decision about your treatment.
No. KioMedine® one uses carboxymethyl-chitosan rather than hyaluronic acid. It is designed as a fluid implant for symptomatic knee osteoarthritis.
Yes. KioMedine® one is designed to be administered as a single intra-articular injection into the affected knee.
It may be considered in some patients with more advanced or difficult-to-treat osteoarthritis, but suitability must be assessed individually. Having severe osteoarthritis does not automatically mean that KioMedine will be appropriate.
KioMedine is not a replacement for knee replacement surgery.
For some patients, non-surgical treatment may be appropriate to help manage symptoms. If knee replacement is clinically indicated, this should be discussed with an appropriate orthopaedic specialist.
There can be some discomfort associated with any knee injection. Your clinician will explain the procedure and the measures used to make treatment as comfortable as reasonably possible.
The manufacturer’s guidance recommends avoiding intense physical activity and heavy loads for 48 hours after the injection, followed by gradual use of the treated knee. Your clinician may provide additional advice based on your circumstances.
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Your consultation and treatment fees should be explained clearly before proceeding.
KioMedine should be administered by an appropriately experienced healthcare professional. If you are based in Southampton, Eastleigh or elsewhere in Hampshire, contact us to discuss your suitability and treatment options.
Living with knee osteoarthritis does not mean you have to simply accept ongoing pain and reduced mobility.
KioMedine® one is one of the treatment options that may be considered for suitable adults with symptomatic knee osteoarthritis.
The first step is a proper assessment.
Book a KioMedine® consultation in Southampton or Eastleigh today and find out whether this treatment could be appropriate for your knee.
[BOOK YOUR KioMedine CONSULTATION]
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KioMedine® one is a regulated medical device intended for the symptomatic treatment of knee osteoarthritis in adults. Treatment suitability varies between individuals and should be determined following an appropriate clinical assessment by a qualified healthcare professional. The information on this page is provided for general educational purposes and does not replace individual medical advice.
